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Erosive duodenitis is usually of peptic origin, caused by chronic exposure to gastric acid and most often a Helicobacter pylori-infection. Histologically gastric mucous cell metaplasia is often found. Erosive duodenitis is a precursor to duodenal ulcer. Crohn´s disease in the duodenum can be macroscopically indistinguishable from peptic erosive duodenitis.
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