The Endoscopy Archives
Melanosis (or Pseudomelanosis) Coli in the RectumClick on any image to get a magnification (and then click "Back" on Your browser). Click here to get back to the index page.
Melanosis coli is a pigmentation of the rectal and colonic mucosa due to use (or abuse) of anthraquinone type laxatives. Histologic specimens show numerous macrophages containing a granular dark pigment in the lamina propria. Withdrawal of the offending laxative, which nearly always can be substituted with a bulk laxative, is sufficient treatment.
April 7, 2007