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Familial Adenomatous Polyposis

  
Familial Polyposis - Adenomas in the Colon
In this disease, there are, from the age of about 15 years, hundreds of adenomas in the colon. In these pictures, however, only a few adenomas are seen, because the patient is only 18 years old at the time of the examination.
  
Familial Polyposis - Adenomas in the Colon
If not treated, one or more of these adenomas will progress into colon cancer, and this disease is always treated with prophylactic colectomy.
 
Familial Polyposis - Adenomas in the Colon
The adenomas are evenly distributed throughout the colon.

Familial Polyposis - Adenoma in the Duodenum
These patients also quite frequently have hyperplastic or adenomatous polyps in the Stomach and adenomas in the duodenum. In this picture is an adenoma in the descending duodenum.

Familial Polyposis, Colectomy Specimen
This is a little part of a surgically removed colon from a patient with familial polyposis, approcimately 5 x 7 centimeters. Dont try to count the polyps, there are about two hundreds of them in this picture.

Familial Polyposis with a Malignant Change, Colectomy Specimen
In this part of a resected colon one sees hundreds of small polyps, and in the middle a large polyp with malignant changes.
  
Gastric Polyps
Patients with Familial Adenomatous Polyposis frequently have gastric and duodenal polyps. The gastric polyps are usually hyperplastic, as in these pictures, and not premalignant.

Gastric Hyperplastic Polyposis in Familial Adenomatous Polyposis

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