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The Old Endoscopy Quiz (and Answer) of the Month July 2006

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Question:
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This middle aged man had a malignant melanoma some years earlier, adequately treated. Now he came to an upper endoscopy as he was found to have a significande iron deficiency anaemia. This is the finding in the stomach. There were two lesions. One was in the border zone between corpus and antrum (here seen in the upper row) and one high up in the corpus (here seen in the lower row). Obviously these are not ordinary stomach adenocarcinomas. What are these findings?
Answer:
Gastric metastatic lesions of a malignant melanoma.
Melanoma is a malignancy the prevalence of which is increasing. Metastases of malignant melanomas can be found in the small intestine, stomach and colon more commonly than the liver. Metastatic lesions can be found years after the initial and treated skin tumour, and the main symptom of gastrointestinal involvment is anaemia.
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Comments:
metastatic malignant melanoma. those lesions represent the endoscopic appearance of the radiographic lesion named "bull eye sign".

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